The year 2020 marks a decade since the term pharmacomicrobiomics was coined (Rizkallah et al., 2010) to crystallize a century-old concept of mutual interactions between humans, drugs, and the microbial world. The human microbiome, with its immense metabolic potential that exceeds …
2020-03-02Researchers at KU Leuven have discovered that a defect in the ATP13A2 gene causes cell death by disrupting the cellular transport of polyamines. When this happens in the part of the brain that controls body movement, it can lead to Parkinson's disease. With more than six million p…
2020-02-28
As a bacterial immune system, CRISPR-Cas is supposed to impose cuts, not suffer them. Yet CRISPR-Cas has been eliminated from many bacterial genomes. How this happens isn't exactly clear, particularly since the presence or absence of CRISPR-Cas systems among and even within bacter…
2020-02-27
The speed and accuracy w ith which current sequencing platforms can produce results are quite staggering compared to methodologies that were being utilized less than ten years ago. Yet, when it comes to making clinical decisions with respect to cancerous tumors, sequencing assays …
2020-02-26In November, researchers announced the results of the first US CRISPR gene therapy. Now the data are out in a peer-reviewed paper, and here are comments on the results from leading researcher Carl June and experts in the field.
2020-02-25Two studies show signs that the introduced DNA is functioning, but it’s too early to know if patients actually benefit.
2020-02-25
Synthetic biology researchers have developed a genome the size of a minimal cell that can copy itself.
2020-02-21
An elaborate system of filaments, liquid droplet dynamics and protein connectors enables the repair of some damaged DNA in the nuclei of cells, researchers have found. The findings further challenge the belief that broken DNA floats aimlessly -- and highlight the value of cross-di…
2020-02-19
Scientists have identified a molecular 'switch' that controls the immune machinery responsible for chronic inflammation in the body. The finding could lead to new ways to halt or even reverse many age-related conditions, from from Alzheimer's and Parkinson's to diabetes and cancer…
2020-02-18
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