Protein editorial assistants are clearing the way for cut-and-paste DNA editors, like CRISPR, to access previously inaccessible genes of interest. Opening up these areas of the genetic code is critical to improving CRISPR efficiency and moving toward futuristic, genetic-based assa…
2020-02-03How anti-CRISPR proteins and other molecules could bolster biosecurity and improve medical treatments.
2020-01-17As the first clinical-trial results trickle in, researchers look ahead to more sophisticated medical applications for genome editing.
2020-01-16Avantor emphasizes the need to address issues of scalability and manufacturability
2020-01-14A research team has reproduced and visualized the earliest developmental steps in human immune cell production in the laboratory and are now set to advance our understanding of childhood diseases like leukemia and autoimmune conditions.
2020-01-13CAR T-cell therapy, a rapidly emerging form of immunotherapy using patients' own cells to treat certain types of cancers, may be a viable treatment option for another life-threatening condition: heart disease. Researchers at Penn Medicine used genetically modified T cells to targe…
2020-01-10Parkinson's disease, Huntington's disease, cystic fibrosis - these and many other fatal hereditary human diseases are genetically transmitted. Many cancers and cardiovascular diseases are also caused by genetic defects. Gene therapy is a promising possibility for the treatment of …
2020-01-09A team has engineered two stem cell lines into “synthetic T cells” that destroy breast cancer cells in vitro.
2020-01-08Systems biologist Steven Wiley says advancements in two areas—single-cell biology and CRISPR—are poised to transform research.
2020-01-08