Researchers have used CRISPR-Cas9 to edit long-lived blood stem cells to reverse the clinical symptoms observed with several blood disorders, including sickle cell disease and beta-thalassemia.
2019-08-19We are all familiar with the common myth that fish have poor memory, but it turns that their DNA has the capacity to hold much more memory than that of humans. Rwesearchers report that memory in the form of 'DNA methylation' is preserved between generations of fish, in contrast to…
2019-08-19Yale researchers have developed a new way to efficiently engineer immune cells, an advance which enhances the ability to fend off cancer and other diseases, they report in the Feb. 25 issue of the journal Nature Methods. A number of new life-saving therapies rely on reconfiguring …
2019-08-19
Using a technique called cryogenic electron microscopy (cryo-EM), a team of scientists from the United States and Canada has captured atomic-level, 3D images of the Cas9 enzyme before and after cutting the DNA. The images reveal new information about how the CRISPR-Cas9 gene-editi…
2019-08-14Biomedical engineers have developed a method for improving the accuracy of the CRISPR genome editing technology by an average of 50-fold. The approach adds a short tail to the guide RNA that folds back and binds onto itself, creating a 'lock' that can only be undone by the targete…
2019-08-14A cure for HIV has been one of the biggest challenges facing the scientific and medical communities for decades. The virus has managed to successfully evade almost every technique that has been thrown up against it. Not only can HIV mutate frequently—making new variants quickly …
2019-08-02Last month, the US Patent and Trademark Officereignited the infamous CRISPR patent disputewhen it declared interference—overlapping intellectual property—between several pending patents belonging to the University of California and patents already awarded to the Broad Institut…
2019-08-02In a pathbreaking experiment, a 34-year-old mother of four from Mississippi is in the limelight for volunteering to be the subject ofCRISPR-mediated gene editingin the hope of achieving a cure for the painful sickle cell anemia with which she has suffered all her life. 3D Renderin…
2019-08-02The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.
2019-08-02
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