David Liu, PhD, presents in vivo results showing proof-of-principle of base editing in correcting the gene defect responsible for a premature aging genetic disorder in mice.
2020-02-17
In the first clinical study of its kind in the US, researchers used CRISPR to modify CAR T cells to make them more potent against cancer, but the clinical benefits are unknown.
2020-02-14The idea of genetically modifying a patient's own immune cells and deploying them against infections and tumors has been around since the 1980s. But to this day modified T cells are still not as effective as natural T cells and have been only been of limited clinical value. Using …
2020-02-14Immune cells (brown) attack a cancer cell. Using CRISPR could make the immune cells more potent.
2020-02-12Scientists have developed a new TREE method (an acronym short for transient reporter for editing enrichment, or TREE), which allows for bulk enrichment of DNA base-edited cell populations -- and for the first time, high efficiency in human stem cell lines.
2020-02-10Genetically edited immune cells can persist, thrive, and function months after a cancer patient receives them.
2020-02-10To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
2020-02-06It’s now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process.
2020-02-06
DNA-responsive polymer gels used for releasing drugs, encapsulating cells, and much more now have greater adaptability thanks to the Cas12a nuclease.
2020-02-04
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